Lionel Messi and Cristiano Ronaldo are the Only Active Players Among Hundreds of La Liga’s Players, Who are in This All Time List. Starting From 2004 Lionel Messi Has Scored 289 Goals in 321 La Liga Matches, and His Journey Not Stopped Yet. His Goal Scoring Ability Improving with Every game, at the moment he is the also all time scorer for FC Barcelona. David Villa and Cristiano Ronaldo are the two other active players who could make this list.
also see 2015/16 la liga standings here